The organic anion transporter oat family

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Webb214 rader · Organic anion transporting polypeptides (OATPs in humans, Oatps in rodents) are multispecific transporters located in numerous epithelia throughout the body. They … WebbThus, OATs are members of a much larger group of transporters—the SLC22 (solute carrier 22) family—that includes organic cation, carnitine and urate transporters. …

Regulation of organic anion transporters: Role in physiology ...

WebbMentioning: 17 - The aim of this study was to explore whether rhein could enhance the effects of pemetrexed (PTX) on the therapy of non-small-cell lung cancer (NSCLC) and … WebbOrganic anion transporters (OATs) and organic cation transporters (OCTs) are members of the superfamily of transporters, Slc (solute carriers). Most are in the families Slc21 … imej parking contact number

Organo anion transporter family - Wikipedia

WebbFör 1 dag sedan · Organic anion transporters 1 and 3 (OAT1/3) occupy a key role in mediating renal elimination. Kynurenic acid (KYNA) was previously discovered as an … Webb1 juni 2000 · Organic anion transporter (OAT) is an heterogenous family of negatively charged proteins, mainly located in kidneys and the liver, but OAT1/OAT3 are also found … Webb1 sep. 2009 · Organic anion transporters (Oats) are located in the barrier epithelia of diverse organs, where they mediate the absorption and excretion of a wide range of … imej thank you

The organic anion transporter (OAT) family: a systems biology ...

Organo-Anion-Transporter – Wikipedia

Webb1 jan. 2006 · Organic anion transporter (OAT) family Gene name Protein name Tissue distribution Predominant substrates SLC22A6 OAT1 kidney PAH, PGE2, urate, NSAIDs, … WebbThe organic anion transporter (OAT) subfamily, which constitutes roughly half of the SLC22 (solute carrier 22) transporter family, has received a great deal of attention … imek coatingThe organic anion transporter 1 (OAT1) also known as solute carrier family 22 member 6 (SLC22A6) is a protein that in humans is encoded by the SLC22A6 gene. It is a member of the organic anion transporter (OAT) family of proteins. OAT1 is a transmembrane protein that is expressed in the brain, the placenta, the eyes, smooth muscles, and the basolateral membrane of proximal tubular cells o… list of non metallic minerals

"WebbMany UTs and drugs administered to CKD patients are organic anions, which are physiologically eliminated by the organic anion transporter (OAT) system [6,7]. OATs … " - The organic anion transporter oat family

The organic anion transporter oat family

Webb23 juni 2000 · The OAT family represents mainly the renal secretory and reabsorptive pathway for organic anions and is also involved in the distribution of organic anion in the … WebbBxPC-3 and MIA PaCa-2 pancreatic cancer cell lines were used to quantify transcripts of OATP 1B1 and 1B3. Results: OATP 1A2, 1B1, and 1B3 proteins were found ubiquitously …

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WebbThe members of the organic anion transporter (OAT) family are mainly expressed in kidney, liver, placenta, intestine, and brain. These transporters play important roles in the … Webb11 apr. 2024 · Glycine synthase (AMT), a solute organic anion transporter family member (OAT), and fatty acyl-coA reductase (FAR) are predicted to be regulated by multiple …

Webb1 jan. 2015 · Abstract The organic anion transporter (OAT) subfamily, which constitutes roughly half of the SLC22 (solute carrier 22) transporter family, has received a great deal … Webb1 aug. 2001 · The organic anion transporter (OAT) family handles a wide variety of clinically important compounds (antibiotics, nonsteriodal anti-inflammatory drugs, etc.) …

Webbic anion transporter families, e.g. the organic anion trans-porting polypeptide (oatp) family or the Mrp (multidrug resistance-associated protein) family. On the other hand, the … Webb10 juli 2024 · Since, in the Oat3KO, the basolateral transport of organic anions by PT cells is dependent upon the remaining OAT (i.e., OAT1), treatment with probenecid should …

WebbOATs are multispecific organic anion transporters, the substrates of which include both endogenous (e.g. cyclic nucleotides, prostaglandins, urate, dicarboxylates) and …

WebbThe editors have built ATP-Dependent Organic Anion Transporters—Advances in Research and Application: 2013 Edition on the vast information databases of ScholarlyNews.™ … list of non narcotic painkillersWebbThe organic anion transporters ( OAT s), part of the SLC22 superfamily of transporters, are expressed throughout the body. However, the most clinically relevant members of this … list of non life insurance company in nepalWebb1 jan. 2015 · The organic anion transporter (OAT) subfamily, which constitutes roughly half of the SLC22 (solute carrier 22) transporter family, has received a great deal of attention … list of non non biyori episodesWebbGene Family The human SCL22 family of transporters encompasses at least 22 members with an additional six structurally related but not yet assigned genes. ... In Vitro and In … list of non metro city in indiaWebbSchnabolk, G. W., Youngblood, G. L., & Sweet, D. H. (2006). Transport of estrone sulfate by the novel organic anion transporter Oat6 (Slc22a20). imeko tc 11 24 conferenceWebb多選択性有機アニオントランスポーターファミリー (OAT family)の同定と薬物輸送における役割の解析. 記事の概要. 抄録. 引用文献 (50) 著者関連情報. 共有する. 抄録. 薬物トラ … list of non pct countriesWebbThe organic anion transporter (OAT) subfamily, which constitutes roughly half of the SLC22 (solute carrier 22) transporter family, has received a great deal of attention … ime judith surgot francheville